Scientific literature Liver Cancer

[Liver cancer]

[Documents] Tian Ye, Li Wenjia, Qian Zhengming, Gao Wei, etc. The pharmacological experiment and clinical research progress of anti-tumor activity of Cordyceps sinensis. Journal of Shenyang Pharmaceutical University, Vol. 34 No. 10 October 2017: 943-950

[Abstract] The authors mainly summarized and reviewed the pharmacological experimental research and clinical application literature of anti-tumor activity of Cordyceps sinensis and its related products at home and abroad for 35 years. Through the retrieval and summarization of related literatures at home and abroad, it is found that the anti-tumor effect on Cordyceps sinensis mainly focuses on solid tumors such as melanoma, lung cancer, liver cancer and sarcoma, as well as non-solid tumors such as leukemia and lymphoma. The water extract of Cordyceps sinensis fruit body can significantly inhibit the growth and proliferation of human fibroblast HT1080 cells, colon cancer CW-2 cells, breast cancer MA-737 cells, human cervical cancer Hela cells, human nasopharyngeal carcinoma KB cells and laryngeal carcinoma cells. The extract of Cordyceps sinensis has obvious inhibitory effects on prostate cancer PC 3 cells, colon cancer Colon 205 cells, breast cancer MCF 7 cells, African green monkey kidney Vero cells, human amniotic membrane Wish cells and mouse A. sinensis ascitic ascites cancer cells. (Tian Ye, Li Wenjia, Qian Zhengming, Gao Wei et al. Pharmacological experiments and clinical research progress of anti-tumor activity of Cordyceps sinensis. Journal of Shenyang Pharmaceutical University, Vol. 34 No. 10, October 2017: 943-950)

[Document] Wang Zheng, Wu Xue, Liu Jianli, Tang Zhishu. Advances in research on antitumor activity of cordycepin. Chinese Pharmaceutical Journal, August 2015, Vol. 50, No. 16: 1365-1368 / Shaanxi University of Traditional Chinese Medicine, Shaanxi Province Traditional Chinese Medicine Resources Industrialization Collaborative Innovation Center, Shaanxi Provincial Key Laboratory of Traditional Chinese Medicine and New Drug Research, Shaanxi Province, Rheumatology and Tumor Research Center of Traditional Chinese Medicine Preparation Engineering Technology, College of Life Sciences, Northwest University, Key Laboratory of Western Resources and Modern Biotechnology, Ministry of Education, Department of Burns, Xijing Hospital, Fourth Military Medical University

[Abstract] Cordycepin is one of the main active ingredients in traditional Chinese herbal medicines, Cordyceps sinensis and Cordyceps militaris, and has a variety of pharmacological activities. After reviewing domestic and foreign literatures, the authors have inhibited the growth and proliferation of various tumor cells such as leukemia cells, lung cancer, liver cancer, prostate cancer, cervical cancer, colon cancer, testicular stromal tumor, human glioma and thyroid cancer. Its molecular biological mechanism is reviewed. To lay a more comprehensive and in-depth study of the antitumor activity of cordycepin and its molecular biological mechanism. (Wang Zheng, Wu Xue, Liu Jianli, Tang Zhishu. Research progress of anti-tumor activity of cordycepin. Chinese Journal of Pharmacy, Vol. 50, No. 16, August 1365-1368 / Shaanxi University of Traditional Chinese Medicine, Collaborative Innovation of Industrialization of Traditional Chinese Medicine Resources in Shaanxi Province Center, Shaanxi Provincial Key Laboratory of Traditional Chinese Medicine and New Drug Research, Shaanxi Provincial Engineering Research Center for Rheumatology and Tumors, College of Life Sciences, Northwest University, Key Laboratory of Western Resources and Modern Biotechnology, Ministry of Education, Xijing Hospital, Fourth Military Medical University Burns)

[Document] Wan Lingfeng, Xue Boyu. Experimental study on the effective components of Cordyceps sinensis to prevent liver diseases. Northern Pharmacy, 2014, Vol. 11 No. 1: 54-56

[Abstract] Studies have shown that the polysaccharides contained in Cordyceps sinensis have anti-tumor, enhance the phagocytic ability of mononuclear macrophages, promote lymphocyte transformation, anti-oxidation and anti-radiation effects in vitro. The adenosine contained in Cordyceps is believed to be related to the improvement of cardiovascular function. Cordycepin is the main active ingredient of antiviral, antibacterial and antitumor. To analyze the experimental study on the prevention and treatment of liver diseases by Cordyceps sinensis in the past 15 years, Cordyceps sinensis and its active ingredients have good effects on chemical liver injury, immune liver injury, nonalcoholic fatty liver, alcoholic fatty liver, liver fibrosis, cirrhosis and liver cancer. Efficacy. References (Wan Lingfeng, Xue Boyu. Experimental study on the prevention and treatment of liver diseases by active ingredients of Cordyceps sinensis. North Pharmacy, Vol. 11 No. 1, 2014: 54-56)

[Research] Zheng Bing, Xie Fangyi, Cai Guohui, Zhu Rucai et al. Experimental study on the killing effect of Xuefeng Cordyceps on DC-CIK proliferation and HepG-2 cells. Chinese Journal of Immunology, Vol. 31, 2015: 189-192

[Abstract] Xuefeng Cordyceps is closely related to Cordyceps sinensis, and has the same chemical composition and similar effects as adenosine, cordycepin, cordycepic acid and amino acid. Cordyceps militaris enhances its effect on HepG-2 cells by promoting the proliferation of DC-CIK and increasing the number of DC-CIK. (Zheng Bing, Xie Fangyi, Cai Guohui, Zhu Rucai et al. Experimental study on the killing effect of Xuefeng Cordyceps on DC-CIK proliferation and HepG-2 cells. Chinese Journal of Immunology, 2015, Vol. 31: 189-192)